Carlos R, Innerarity S
Br J Anaesth. 1979 Dec;51(12):1159-62. doi: 10.1093/bja/51.12.1159.
The effect of premedication upon the induction of anaesthesia with etomidate was studied in 74 adult patients undergoing elective orthopaedic surgery. Premedication with fentanyl plus atropine or with diazepam plus atropine decreased the frequency of involuntary muscle movements without modifying the pattern of the circulatory effects of etomidate, although fentanyl increased the frequency of apnoea. Pain at the site of injection was not modified by premedication.
在74例接受择期骨科手术的成年患者中，研究了术前用药对依托咪酯诱导麻醉的影响。术前使用芬太尼加阿托品或地西泮加阿托品可降低不自主肌肉运动的频率，且不改变依托咪酯的循环效应模式，尽管芬太尼会增加呼吸暂停的频率。术前用药并未改变注射部位的疼痛情况。
