Antonios W R, Inglis M D, Lees N W
Anaesthesia. 1984 Aug;39(8):812-5. doi: 10.1111/j.1365-2044.1984.tb06532.x.
Etomidate was used to induce anaesthesia in 50 healthy subjects undergoing minor gynaecological surgery who were randomly divided into two groups, one receiving alfentanil 8 micrograms/kg intravenously immediately prior to induction of anaesthesia with etomidate, and the other halothane as required to maintain adequate anaesthesia. There was a highly significant reduction in the incidence of myoclonia and involuntary movement and significant reduction of pain on injection in the alfentanil group. Tests of recovery performed in the 60 minutes following anaesthesia suggested that supplementation with alfentanil led to more rapid recovery than halothane.
依托咪酯用于50例接受小型妇科手术的健康受试者的麻醉诱导,这些受试者被随机分为两组,一组在依托咪酯麻醉诱导前立即静脉注射8微克/千克阿芬太尼,另一组按需使用氟烷以维持足够的麻醉。阿芬太尼组的肌阵挛和不自主运动发生率显著降低,注射时的疼痛也显著减轻。麻醉后60分钟进行的恢复测试表明,补充阿芬太尼比氟烷导致更快的恢复。