拉贝洛尔治疗高血压患者心绞痛的开放性评估。
Open evaluation of labetalol in the treatment of angina pectoris occurring in hypertensive patients.
作者信息
Besterman E M, Spencer M
出版信息
Br J Clin Pharmacol. 1979;8(Suppl 2):205S-209S.
Abstract
1 In nine hypertensive subjects with angina pectoris, labetalol diminished the incidence of chest pain occurring spontaneously or induced by exercise. 2 Labetalol lowered BP in all subjects. 3 Exercise tolerance at maximum levels was increased by labetalol. 4 Improved cardiac function by labetalol may be related to decreased afterload on the left ventricle, and diminished oxygen utilization by the myocardium.
摘要
- 在9名患有心绞痛的高血压患者中，拉贝洛尔降低了自发性或运动诱发的胸痛发生率。2. 拉贝洛尔使所有患者的血压降低。3. 拉贝洛尔提高了最大运动耐量。4. 拉贝洛尔改善心脏功能可能与降低左心室后负荷及减少心肌氧利用有关。
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本文引用的文献
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Br J Clin Pharmacol. 1976 Aug;3(4 Suppl 3):721-3.
3
Reflex increase in coronary vascular resistance in patients with ischemic heart disease.缺血性心脏病患者冠状动脉血管阻力的反射性增加。
N Engl J Med. 1976 Dec 9;295(24):1333-7. doi: 10.1056/NEJM197612092952401.
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