拉贝洛尔输注用于急性心肌梗死合并系统性高血压。
Labetalol infusion in acute myocardial infarction with systemic hypertension.
作者信息
Marx P G, Reid D S
出版信息
Br J Clin Pharmacol. 1979;8(Suppl 2):233S-238S.
Abstract
1 Fifteen patients with suspected acute myocardial infarction and systemic BP of greater than 160/110 mmHg were treated with an incremental infusion of labetalol. 2 Systemic BPs were safely and effectively lowered to less than 130 mm Hg systolic or 90 mmHg diastolic in all pateints. 3 Heart rate, mean pulmonary artery wedge pressure cardiac index and stroke work index were significantly reduced. 4 The dose of labetalol varied from 30 mg--440 mg and was significantly higher (mean 295 mg) in those patients with pre-existing systemic hypertension compared with others (mean 133 mg). 5 No side-effects occurred and all patients survived to leave hospital.
摘要
15例疑似急性心肌梗死且收缩压大于160/110 mmHg的患者接受了拉贝洛尔递增输注治疗。
所有患者的收缩压均安全有效地降至130 mmHg以下或舒张压降至90 mmHg以下。
心率、平均肺动脉楔压、心脏指数和每搏功指数均显著降低。
拉贝洛尔剂量为30 mg至440 mg，与其他患者（平均133 mg）相比，既往有系统性高血压的患者剂量显著更高（平均295 mg）。
未出现副作用，所有患者均存活出院。
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