West R H, Barnett A J
Br J Ophthalmol. 1979 Dec;63(12):845-7. doi: 10.1136/bjo.63.12.845.
Thirty-eight patients with scleroderma (progressive systemic sclerosis) without renal failure were subjected to detailed clinical ophthalmic assessment. Abnormalities were frequent. However, many of these, including lens opacities, vitreous frosting, and arteriosclerotic changes, were considered to be age-related, and there were various incidental changes. Posterior subcapsular lens opacities in one patient were probably corticosteroid-induced. Changes related to scleroderma included eyelid abnormalities (stiffness or tightness in 11, telangiectasia in 8), deficient tear secretion (14 cases), and conjunctival abnormalities (injection 19 cases, vascular sludging 27 cases). Iris light reflux (6 cases) was possibly related to scleroderma. The changes related to scleroderma occurred in the 3 types classified according to the extent of skin involvement.
对38例无肾衰竭的硬皮病（进行性系统性硬化症）患者进行了详细的临床眼科评估。异常情况很常见。然而，其中许多异常，包括晶状体混浊、玻璃体混浊和动脉硬化改变，被认为与年龄有关，还有各种偶然出现的变化。1例患者的后囊下晶状体混浊可能是由皮质类固醇引起的。与硬皮病相关的改变包括眼睑异常（11例僵硬或紧绷，8例毛细血管扩张）、泪液分泌不足（14例）和结膜异常（19例充血，27例血管淤滞）。虹膜光反射异常（6例）可能与硬皮病有关。与硬皮病相关的改变出现在根据皮肤受累程度分类的3种类型中。
