Kozikowska Małgorzata, Luboń Wojciech, Kucharz Eugeniusz J, Mrukwa-Kominek Ewa
Department of Ophthalmology, Professor K. Gibinski University Clinical Center of the Medical University of Silesia, Katowice, Poland.
Department of Ophthalmology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice, Poland.
Reumatologia. 2020;58(6):401-406. doi: 10.5114/reum.2020.102004. Epub 2020 Dec 23.
Systemic sclerosis (SSc) is a rare, chronic autoimmune disease with unknown etiology. Its prominent features are fibrosis, vasculopathy and impaired immune response. Disease can also affect eyes leading to various findings in ophthalmological examination. The objective of this study was to determine the prevalence and type of ocular involvement in patients with SSc. A systematic literature review was conducted using electronic databases. A combination of following keywords was used: "systemic sclerosis" and ophthalmology-related search terms, including the keywords "eye", "ocular" and "ophthalmic". In conclusion, eyelid and conjunctival abnormalities and dry eye disease are among the most common ocular manifestations of SSc. Their diversity is connected to complexity of the disease.
系统性硬化症（SSc）是一种病因不明的罕见慢性自身免疫性疾病。其突出特征为纤维化、血管病变和免疫反应受损。该疾病还可累及眼睛，导致眼科检查出现各种结果。本研究的目的是确定系统性硬化症患者眼部受累的患病率及类型。我们使用电子数据库进行了一项系统的文献综述。使用了以下关键词组合：“系统性硬化症”以及与眼科相关的检索词，包括关键词“眼睛”“眼部的”和“眼科的”。总之，眼睑和结膜异常以及干眼症是系统性硬化症最常见的眼部表现。它们的多样性与该疾病的复杂性相关。
