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出生前人体肝脏中的微量元素含量。

Contents of trace elements in the human liver before birth.

作者信息

Meinel B, Bode J C, Koenig W, Richter F W

出版信息

Biol Neonate. 1979;36(5-6):225-32. doi: 10.1159/000241233.

DOI:10.1159/000241233
PMID:526487
Abstract

A multielement analysis was carried out in nine fetal livers (age: 23 weeks of gestation to term) in comparison to an adult control group (n = 37). 15 elements (phosphorus to lead) were analyzed by proton-induced X-ray emission (PIXE). Significant differences between the two groups, expressed as ratios (R) of fetal to adult liver values were observed for copper (R = 16), zinc (R = 2.0), iron (R = 1.5), calcium (R = 1.34), selenium (R = 1.22), manganese (R = 0.7), and molybdenum (R = 0.13). An interesting point seems to be the inverse relation of copper and molybdenum. The negative correlation of these two trace elements which is known from animal experiments has now been confirmed in the human liver.

摘要

对9个胎儿肝脏(孕周:23周直至足月)进行了多元素分析,并与一个成人对照组(n = 37)进行比较。通过质子诱导X射线发射(PIXE)分析了15种元素(从磷到铅)。两组之间存在显著差异,以胎儿肝脏与成人肝脏值的比率(R)表示,铜(R = 16)、锌(R = 2.0)、铁(R = 1.5)、钙(R = 1.34)、硒(R = 1.22)、锰(R = 0.7)和钼(R = 0.13)呈现出这种差异。一个有趣的点似乎是铜和钼的反向关系。这两种微量元素在动物实验中已知的负相关关系现在已在人类肝脏中得到证实。

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