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巯基乙酸钠在用于梭状芽孢杆菌孢子复苏的培养基中的抑制特性研究。

An investigation of the inhibitory properties of sodium thioglycollate in media for the recovery of clostridial spores.

作者信息

Hibbert H R, Spencer R

出版信息

J Hyg (Lond). 1970 Mar;68(1):131-5. doi: 10.1017/s0022172400028588.

DOI:10.1017/s0022172400028588
PMID:5266580
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2130793/
Abstract

The effect of various concentrations of sodium thioglycollate (0-0.05%) on the recovery of spores of four strains of clostridia was investigated. The results showed that thioglycollate at a concentration of 0.01% can be inhibitory to some clostridia. However, the results also indicated that the inhibitory effect is dependent upon the composition of the growth medium. The presence of glucose appeared to be particularly important in reducing the inhibitory effect. These findings support the view that the use of sodium thioglycollate in sterility test media should be discontinued.

摘要

研究了不同浓度的巯基乙酸钠(0 - 0.05%)对四种梭菌菌株孢子复苏的影响。结果表明,浓度为0.01%的巯基乙酸钠对某些梭菌有抑制作用。然而,结果也表明这种抑制作用取决于生长培养基的组成。葡萄糖的存在似乎对降低抑制作用尤为重要。这些发现支持了应停止在无菌试验培养基中使用巯基乙酸钠的观点。

相似文献

1
An investigation of the inhibitory properties of sodium thioglycollate in media for the recovery of clostridial spores.巯基乙酸钠在用于梭状芽孢杆菌孢子复苏的培养基中的抑制特性研究。
J Hyg (Lond). 1970 Mar;68(1):131-5. doi: 10.1017/s0022172400028588.
2
Studies on the inhibitory properties of sodium thioglycollate on the germination of wet spores of clostridia.巯基乙酸钠对梭状芽孢杆菌湿孢子萌发抑制特性的研究。
J Hyg (Lond). 1968 Jun;66(2):269-72. doi: 10.1017/s0022172400041127.
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Recovery of spores of Clostridium difficile altered by heat or alkali.经加热或碱处理后艰难梭菌孢子的复苏
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[Enumeration and identification of Clostridium from stools treated with the thioglycollate-lysozyme method].[用硫乙醇酸盐-溶菌酶法处理粪便中梭菌的计数与鉴定]
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Zentralbl Bakteriol Orig. 1969 Dec;212(1):109-14.
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[A medium for the differentiation of some pathogenic clostridia].
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本文引用的文献

1
A Study of Fluid Thioglycollate Medium for the Sterility Test.用于无菌检查的液体硫乙醇酸盐培养基的研究。
J Bacteriol. 1946 Jan;51(1):19-32.
2
The technique of sterility testing.无菌检测技术。
J Pharm Pharmacol. 1956 Aug;8(8):573-88. doi: 10.1111/j.2042-7158.1956.tb12189.x.
3
[Study of media used for the counting of spores of anaerobic bacteria in alimentary microbiology].[用于肠道微生物学中厌氧菌孢子计数的培养基研究]
Ann Inst Pasteur Lille. 1965;16:147-56.
4
Studies on the inhibitory properties of sodium thioglycollate on the germination of wet spores of clostridia.巯基乙酸钠对梭状芽孢杆菌湿孢子萌发抑制特性的研究。
J Hyg (Lond). 1968 Jun;66(2):269-72. doi: 10.1017/s0022172400041127.