Penney M D, Murphy D, Walters G
Br Med J. 1979 Dec 8;2(6203):1474-6. doi: 10.1136/bmj.2.6203.1474.
In a patient with hyponatraemia associated with acute idiopathic polyneuritis plasma concentrations of antidiuretic hormone increased when hypertonic saline was infused intravenously, and urine osmolality rose concomitantly. A water load was excreted normally, while the plasma remained extremely hypo-osmolal. It is concluded that osmoregulation was functioning normally but was set abnormally low, possibly owing to a disturbance of the peripheral volume receptors.
在一名患有与急性特发性多神经炎相关的低钠血症患者中，静脉输注高渗盐水时抗利尿激素的血浆浓度升高，同时尿渗透压也随之升高。水负荷正常排出，而血浆仍处于极低渗状态。得出的结论是，渗透调节功能正常，但设定值异常低，可能是由于外周容量感受器紊乱所致。
