小剂量人成纤维细胞干扰素注射治疗尖锐湿疣的效果。一项初步研究。
Effect of injections of small doses of human fibroblast interferon into genital warts. A pilot study.
作者信息
Scott G M, Csonka G W
出版信息
Br J Vener Dis. 1979 Dec;55(6):442-5. doi: 10.1136/sti.55.6.442.
Abstract
Eleven male patients with genital warts were given injections of fibroblast interferon (300 u) and placebo into the bases of two similar warts. The changes in size of the treated warts compared with that of the controls suggested that interferon did inhibit the growth of the warts. The dose given was probably insufficient for a dramatic effect. In one patient, however, a wart on the penile shaft was injected with interferon and did disappear within two weeks whereas an untreated meatal wart increased in size.
摘要
11名患有尖锐湿疣的男性患者，在两个相似疣体的基底部分别注射成纤维细胞干扰素（300单位）和安慰剂。与对照组相比，治疗后疣体大小的变化表明干扰素确实抑制了疣体的生长。所给予的剂量可能不足以产生显著效果。然而，在一名患者中，阴茎干上的一个疣体注射干扰素后在两周内消失，而未治疗的尿道口疣体则增大。
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Effect of injections of small doses of human fibroblast interferon into genital warts. A pilot study.小剂量人成纤维细胞干扰素注射治疗尖锐湿疣的效果。一项初步研究。
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本文引用的文献
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Natural history of genital warts.尖锐湿疣的自然病史。
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Demonstration of virus particles in human genital warts.人类生殖器疣中病毒颗粒的显示。
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On the mechanism of enhancement of human interferon production by actinomycin D and cycloheximide.放线菌素D和环己酰亚胺增强人干扰素产生的机制
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Effect of human fibroblast interferon on vaccination in volunteers.人成纤维细胞干扰素对志愿者接种疫苗的影响。
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