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Carcinostatic activity of thiosemicarbazones of formyl heteroaromatic compounds. VI. 1-Formylisoquinoline derivatives bearing additional ring substituents, with notes on mechanism of action.

作者信息

French F A, Blanz E J, DoAmaral J R, French D A

出版信息

J Med Chem. 1970 Nov;13(6):1117-24. doi: 10.1021/jm00300a024.

DOI:10.1021/jm00300a024
PMID:5273757
Abstract
摘要

相似文献

1
Carcinostatic activity of thiosemicarbazones of formyl heteroaromatic compounds. VI. 1-Formylisoquinoline derivatives bearing additional ring substituents, with notes on mechanism of action.
J Med Chem. 1970 Nov;13(6):1117-24. doi: 10.1021/jm00300a024.
2
Carcinostatic activity of thiosemicarbazones of formyl heteroaromatic compounds. VII. 2-Formylpyridine derivatives bearing additional ring substituents.甲酰基杂芳族化合物的硫代氨基脲的抗癌活性。VII. 带有额外环取代基的2-甲酰基吡啶衍生物。
J Med Chem. 1970 Nov;13(6):1124-30. doi: 10.1021/jm00300a025.
3
The carcinostatic activity of thiosemicarbazones of formyl heteroaromatic compounds. 3. Primary correlation.甲酰基杂环芳香化合物硫代氨基脲的抑癌活性。3. 初步相关性。
J Med Chem. 1966 Jul;9(4):585-9. doi: 10.1021/jm00322a032.
4
The carcinostatic activity of 5-hydroxy-2-formylpyridine thiosemicarbazone.5-羟基-2-甲酰基吡啶硫代半卡巴腙的抑癌活性。
Cancer Res. 1968 Dec;28(12):2419-22.
5
Potential antitumor agents. 3. Sodium salts of alpha-[N]-heterocyclic carboxaldehyde thiosemicarbazones.潜在的抗肿瘤剂。3. α-[N]-杂环羧醛缩氨基硫脲的钠盐。
J Pharm Sci. 1968 Nov;57(11):1948-51. doi: 10.1002/jps.2600571125.
6
The carcinostatic activity of alpha-(N)-heterocyclic carboxaldehyde thiosemicarbazones. II. 3-Hydroxypyridine-2-carboxaldehyde thiosemicarbazone.α-（N）-杂环羧醛缩氨基硫脲的抑癌活性。II. 3-羟基吡啶-2-羧醛缩氨基硫脲。
Cancer Res. 1966 Aug;26(8):1638-40.
7
Potential antitumor agents. II. Effects of modifications in the side chain of 1-formylisoquinoline thiosemicarbazone.潜在的抗肿瘤剂。II. 1-甲酰基异喹啉硫代半卡巴腙侧链修饰的影响。
J Med Chem. 1969 Sep;12(5):771-4. doi: 10.1021/jm00305a011.
8
Alpha-(N)-formylheteroaromatic thiosemicarbazones. Inhibition of tumor-derived ribonucleoside diphosphate reductase and correlation with in vivo antitumor activity.α-（N）-甲酰基杂芳基硫代半卡巴腙。对肿瘤来源的核糖核苷二磷酸还原酶的抑制作用及其与体内抗肿瘤活性的相关性。
J Med Chem. 1974 Feb;17(2):172-81. doi: 10.1021/jm00248a006.
9
Elucidation of the structure of the antineoplastic agents, 2-formylpyridine and 1-formylisoquinoline thiosemicarbazones.抗肿瘤药物2-甲酰基吡啶和1-甲酰基异喹啉硫代氨基脲的结构解析
J Med Chem. 1977 Mar;20(3):447-9. doi: 10.1021/jm00213a024.
10
Kethoxal bis(thiosemicarbazone). I. Effects against experimental tumors.乙二醛双（硫代半卡巴腙）。I. 对实验性肿瘤的作用。
Cancer Res. 1965 Oct;25(9):1410-6.

引用本文的文献

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Isoquinoline thiosemicarbazone displays potent anticancer activity with efficacy against aggressive leukemias.异喹啉硫代半卡巴腙具有强大的抗癌活性，对侵袭性白血病有效。
RSC Med Chem. 2020 Feb 24;11(3):392-410. doi: 10.1039/c9md00594c. eCollection 2020 Mar 1.
2
Cytotoxic and Antitumour Studies of Acetoacetanilide N(4)-methyl(phenyl)thiosemicarbazone and its Transition Metal Complexes.乙酰乙酰苯胺N(4)-甲基（苯基）硫代半卡巴腙及其过渡金属配合物的细胞毒性和抗肿瘤研究
Indian J Pharm Sci. 2015 Nov-Dec;77(6):655-60. doi: 10.4103/0250-474x.174981.
3
Activity of 2-acetylpyridine thiosemicarbazones against Trypanosoma rhodesiense in vitro.
2-乙酰基吡啶硫代半卡巴腙对罗德西亚锥虫的体外活性
Antimicrob Agents Chemother. 1980 Aug;18(2):317-22. doi: 10.1128/AAC.18.2.317.
4
Inhibition of RNA-dependent DNA polymerase of Rous sarcoma virus by thiosemicarbazones and several cations.硫代氨基脲和几种阳离子对劳氏肉瘤病毒RNA依赖性DNA聚合酶的抑制作用。
Proc Natl Acad Sci U S A. 1973 Jan;70(1):164-8. doi: 10.1073/pnas.70.1.164.
5
Antifungal and antitumor activity of heterocyclic thiosemicarbazones and their metal complexes: current status.杂环缩氨基硫脲及其金属配合物的抗真菌和抗肿瘤活性：现状
Biometals. 1992 Summer;5(2):121-6. doi: 10.1007/BF01062223.