Mauderly J L
Exp Aging Res. 1979 Dec;5(6):497-508. doi: 10.1080/03610737908257224.
The breathing pattern, subdivisions of lung volume and quasistatic pressure-volume relationships of 15 and 65 week old hamsters (Mesocricetus auratus) anesthetized with halothane were measured by plethysmography. Body weights, tidal volumes and minute volumes of the younger and older groups were nearly identical. All lung volumes were larger in the older hamsters but there were no significant age-related differences in the relative proportions of lung volume subdivisions. Quasistatic lung compliance was greater in the older group but differences in pressure-volume relationships were not significant when volume was expressed as percent of total lung capacity. It appears that hamster lungs undergo significant volume changes with age during adulthood, but the pattern of change is different from that observed in man and dogs.
通过体积描记法测量了用氟烷麻醉的15周龄和65周龄仓鼠（金黄地鼠）的呼吸模式、肺容积细分以及准静态压力-容积关系。年轻组和老年组的体重、潮气量和分钟通气量几乎相同。老年仓鼠的所有肺容积都更大，但肺容积细分的相对比例在年龄上没有显著差异。老年组的准静态肺顺应性更大，但当容积以总肺容量的百分比表示时，压力-容积关系的差异并不显著。成年期仓鼠肺似乎会随着年龄增长发生显著的容积变化，但变化模式与人类和犬类不同。
