Emori T, Takahashi M, Nagase S, Yoshida T
Jikken Dobutsu. 1979 Oct;28(4):531-5.
Increase of lactate dehydrogenase (EC 1.1.1.28) and creatine kinase (EC 2.7.3.2) in serum and plasma level during blood clotting was compared in R. rattus flavitectus (black rat) and R. norvegicus (albino rat). Both the enzyme level increased by the release from platelets in process of clotting in rat as previously described (Emori T., Takahashi M. and Nagase S. (1978) Exp. Animals, 27, 167), but the change in black rat was very slight. Owing to search for the reason to prove the difference in this phenomenon, physiological and chemical properties of blood from both the animals were compared, and it was demonstrated that the content of plasma fibrinogen in black rat is higher than that in albino rat, while the platelet number contained in each ml of blood and the enzyme activities in each platelet are not different between them. The analysis of the membrane proteins from platelets of both the animals by SDS-polyacrylamide gel electrophoresis showed that the fractional value of glycoproteins was found to be different between them.
比较了黄胸鼠（黑鼠）和褐家鼠（白鼠）在血液凝固过程中血清和血浆中乳酸脱氢酶（EC 1.1.1.28）和肌酸激酶（EC 2.7.3.2）水平的升高情况。如先前所述（Emori T., Takahashi M. 和 Nagase S. (1978) Exp. Animals, 27, 167），大鼠在凝血过程中，这两种酶的水平均因血小板释放而升高，但黑鼠的变化非常轻微。为了寻找这种现象差异的原因，比较了两种动物血液的生理和化学特性，结果表明黑鼠血浆纤维蛋白原含量高于白鼠，而每毫升血液中的血小板数量以及每个血小板中的酶活性在两者之间并无差异。通过SDS - 聚丙烯酰胺凝胶电泳对两种动物血小板的膜蛋白进行分析，结果显示它们的糖蛋白分数值存在差异。
