Shibata S, Kobayashi B
Thromb Haemost. 1978 Jun 30;39(3):701-6.
The creatine kinase (CK) activity in rat plasma was found to be correlated with that in serum or platelets. Rat serum contained higher activity not only of CK but also of lactate dehydrogenase than the corresponding plasma. The plasma CK activity decreased with increasing age of rats. Only the brain-type isoenzyme of CK was found in plasma, serum and platelets. Contamination of brain-type with muscle-type isoenzyme was detected in rather exceptional cases in which the activity was high among old rats. These results suggest the possible contribution of blood platelets to the CK activity of circulating plasma as well as to the activity in serum in rats.
研究发现，大鼠血浆中的肌酸激酶（CK）活性与血清或血小板中的肌酸激酶活性相关。大鼠血清中不仅CK活性高于相应的血浆，乳酸脱氢酶活性也更高。血浆CK活性随大鼠年龄增长而降低。在血浆、血清和血小板中仅发现脑型CK同工酶。在老年大鼠中活性较高的极少数情况下，检测到脑型同工酶被肌肉型同工酶污染。这些结果表明，血小板可能对大鼠循环血浆中的CK活性以及血清中的CK活性有贡献。
