Sialic acid in human semen.

Sialic acid of seminal fluid of eighty two human subjects has been studied in relation to infertility. Normozoospermic group had highest sialic acid content (94 mgm/100 ml of the fluid) and was significantly different from other groups. The lowest sialic acid level was observed in necrozoospermic group (54 mgm/100 ml of the fluid). Azoospermic (62 mgm/100 ml) and vasectomised group (73 mgm/100 ml) had 33 and 22 percent less sialic acid level respectively than normozoospermic group. For the pooled observation sialic acid was found to be correlated (r = 0.282, significant at 5 percent level) with the total sperm count.