Halliday D, Hesp R, Stalley S F, Warwick P, Altman D G, Garrow J S
Int J Obes. 1979;3(1):1-6.
Resting metabolic rate was measured in 22 women with varying degrees of obesity. Body composition was estimated from total body potassium and from total body water, and creatinine excretion in urine was measured over a period of three weeks while the patients were on a creatinine and creatine-free reducing diet. Resting metabolic rate was highly significantly correlated with body weight, surface area, creatinine excretion and lean body mass calculated either from potassium or water measurements (P less than 0.001). Correlation with adipose tissue was less strong, and when multiple regression of both fat and lean on metabolic rate was performed, the relationship was seen to depend mostly on the mass of lean rather than adipose tissue. In obese people the water content of fat-free tissue is greater than that in normal subjects, so it is not valid to assume that fat content can be calculated accurately from a measurement of total body water.
对22名不同程度肥胖的女性测量了静息代谢率。通过全身钾含量和全身水含量估算身体成分，并在患者进行无肌酐和肌酸的减肥饮食的三周时间内测量尿肌酐排泄量。静息代谢率与体重、体表面积、肌酐排泄量以及通过钾或水测量计算出的瘦体重高度显著相关（P小于0.001）。与脂肪组织的相关性较弱，当对脂肪和瘦体重与代谢率进行多元回归分析时，发现这种关系主要取决于瘦体重而非脂肪组织的质量。在肥胖人群中，无脂肪组织的含水量高于正常受试者，因此假设通过测量全身水含量就能准确计算脂肪含量是无效的。
