Ritossa F, Malva C, Boncinelli E, Graziani F, Polito L
Proc Natl Acad Sci U S A. 1971 Jul;68(7):1580-4. doi: 10.1073/pnas.68.7.1580.
Those Drosophila bobbed males whose progeny exhibit the phenomenon of "rDNA magnification" are shown to have higher rates of rRNA synthesis than normal males. Further evidence that the magnification process is characterized by a stepwise accumulation of rDNA was obtained. A working hypothesis to explain the magnification process is advanced.
那些后代表现出“rDNA 扩增”现象的果蝇截毛雄蝇,其 rRNA 合成速率高于正常雄蝇。进一步的证据表明,扩增过程的特征是 rDNA 的逐步积累。提出了一个解释扩增过程的可行假说。