Malva C, La Volpe A, Gargiulo G
Mol Gen Genet. 1980;180(3):511-5. doi: 10.1007/BF00268054.
Unequal mitotic sister strand crossing over has been evoked to explain the occurrence of phenotypically bb+ males in the progeny of phenotypically bobbed males during magnification. If this is the case, complementary bbl loci should be obtained together with the bb+. To test this hypothesis we compared the frequency of bb lethal mutations in the sperms of bb males with the percentages of phenotypically bb+ males obtained during magnification of these bb males. We then compared these values with those occurring in phenotypically bb+ control males. We found that, while the number of bb+ males obtained during magnification, though variable, is high, the bb lethal mutation occurs at a very low frequency in all the genetic conditions, whatever the phenotype of the parental male.
在放大过程中，不等有丝分裂姐妹染色单体交叉互换被用来解释表型为截毛的雄性后代中出现表型为bb +雄性的现象。如果是这种情况，互补的bbl位点应该与bb +一起获得。为了验证这一假设，我们将bb雄性精子中bb致死突变的频率与这些bb雄性放大过程中获得的表型为bb +雄性的百分比进行了比较。然后，我们将这些值与表型为bb +的对照雄性中出现的值进行了比较。我们发现，虽然放大过程中获得的bb +雄性数量虽然可变但很高，但无论亲本雄性的表型如何，bb致死突变在所有遗传条件下的发生频率都非常低。
