Kollinger G, Schwab M, Anders F
J Cancer Res Clin Oncol. 1979;95(3):239-46. doi: 10.1007/BF00410645.
5-Bromodeoxyuridine (BrdUrd) injected into the muscular tissue of fish bearing melanoma or neuroblastoma induces the production of virus-like particles in these tumors. The particles in the melanoma are morphologically similar to papovaviruses of polyoma-type, those in the neuroblastoma resemble oncornaviruses of B- and C-type.
将5-溴脱氧尿苷(BrdUrd)注射到患有黑色素瘤或神经母细胞瘤的鱼的肌肉组织中,会在这些肿瘤中诱导产生病毒样颗粒。黑色素瘤中的颗粒在形态上类似于多瘤型乳头瘤病毒,神经母细胞瘤中的颗粒则类似于B型和C型肿瘤病毒。