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多发性硬化症在英格兰、威尔士及欧洲部分地区的分布情况。

Multiple sclerosis distribution in England and Wales and parts of Europe.

作者信息

Stocks P

出版信息

J Hyg (Lond). 1971 Sep;69(3):373-89. doi: 10.1017/s0022172400021628.

Abstract

Scotland and Ireland have the highest death rates from multiple sclerosis and high rates are recorded in an area extending south-eastward from Britain through central Europe. The rates tend to diminish with rising latitude and longitude. In England and Wales the county boroughs with notably high rates during 1958-67 were mostly textile towns with cotton and wool mills, situated in the area recording the lowest average levels of sunshine. In the London area mortality from multiple sclerosis was high in those western boroughs and adjacent counties most exposed to the noise of aircraft using the airports of London. The geographical pattern in England suggests that noise and vibration of particular kinds may be a factor in causation along with a climatic factor, but this hypothesis is speculative until further evidence is found to support it.

摘要

苏格兰和爱尔兰的多发性硬化症死亡率最高,并且从英国向东南延伸至中欧的一个区域也记录到了高发病率。发病率往往随着纬度和经度的增加而降低。在英格兰和威尔士,1958年至1967年期间发病率显著较高的自治市大多是有棉纺厂和毛纺厂的纺织城镇,位于日照平均水平最低的地区。在伦敦地区,使用伦敦机场的飞机噪音影响最大的那些西部自治市及邻近郡县,多发性硬化症的死亡率很高。英格兰的地理分布模式表明,特定类型的噪音和振动可能与气候因素一起成为致病的一个因素,但在找到进一步证据支持这一假设之前,它只是一种推测。

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引用本文的文献

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The prevalence of multiple sclerosis in south east Wales.威尔士东南部多发性硬化症的患病率。
J Neurol Neurosurg Psychiatry. 1988 Dec;51(12):1520-4. doi: 10.1136/jnnp.51.12.1520.

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GEOGRAPHIC AND CLIMATIC ASPECTS OF MULTIPLE SCLEROSIS; A REVIEW OF CURRENT HYPOTHESES.
Am J Public Health Nations Health. 1964 Apr;54(4):588-97. doi: 10.2105/ajph.54.4.588.
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MULTIPLE SCLEROSIS AND POLIOMYELITIS.多发性硬化症与小儿麻痹症
Lancet. 1963 Nov 2;2(7314):917-21. doi: 10.1016/s0140-6736(63)90624-x.
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Correlation of the geographic distribution of multiple sclerosis with cosmic-ray intensities.
Acta Psychiatr Scand Suppl. 1960;35(147):108-31. doi: 10.1111/j.1600-0447.1960.tb08673.x.
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Epidemiological aspects of multiple sclerosis.多发性硬化症的流行病学特征
Proc R Soc Med. 1968 Sep;61(9):937-40. doi: 10.1177/003591576806100934.

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