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RNA二级结构预测

Prediction of RNA secondary structure.

作者信息

Delisi C, Crothers D M

出版信息

Proc Natl Acad Sci U S A. 1971 Nov;68(11):2682-5. doi: 10.1073/pnas.68.11.2682.

Abstract

Calculations of the free energy required to close single-strand loops by formation of a base pair in double-helical nucleic acids are reported. These results can be used to estimate the free energy of particular secondary structures for a given RNA molecule under conditions of high-salt concentration.

摘要

报告了通过在双螺旋核酸中形成碱基对来闭合单链环所需自由能的计算结果。这些结果可用于估计给定RNA分子在高盐浓度条件下特定二级结构的自由能。

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