Eyring H, Stover B J, Brown R A
Proc Natl Acad Sci U S A. 1971 Aug;68(8):1670-2. doi: 10.1073/pnas.68.8.1670.
In papers I, II, and III of this series the steady-state theory of mutations was developed and applied to the extensive data on the effect of radiation on beagles acquired here during the past twenty years. In this paper the theory is used to interpret H. B. Dorn's data on the incidence of 21 kinds of cancer in both male and female Americans. The theory shows the nature of the heterogeneity in the population of various disorders. The agreement found confirms the steady-state theory of mutations in an interesting way.
在本系列的论文I、II和III中，我们提出了突变的稳态理论，并将其应用于过去二十年在此获得的关于辐射对小猎犬影响的大量数据。在本文中，该理论用于解释H.B.多恩关于美国男性和女性21种癌症发病率的数据。该理论揭示了各种疾病人群中异质性的本质。所发现的一致性以一种有趣的方式证实了突变的稳态理论。
