Adebonojo S A, Adebo O, Osinowo O
J Natl Med Assoc. 1979 Jul;71(7):687-91.
Between April 1975 and March 1978, 54 patients were treated for bronchiectasis at the University College Hospital, Ibadan. The sex distribution was equal and ages of the patients ranged from five to 67 years with a peak incidence of the disease in the third and fourth decades of life.One third of the patients had tuberculous bronchiectasis with destroyed left lung syndrome, another third had chronic sinusitis, while nine percent had sickle cell hemoglobinopathy. One case of Kartagener syndrome, pulmonary aspergillosis, poliomyelitis, and aspiration of a foreign body were associated with bronchiectasis.Factors influencing the clinical course and prognosis of this disease in this environment include life threatening hemoptysis, bilateral disease, associated lung abscess or empyema, malnutrition, and chronic anemia.Twenty-six patients were treated conservatively with one death, while 28 patients were treated surgically with three deaths. Twenty percent of the surgical patients developed recurrent bronchiectasis within one to 31/2 years, in lobes which were bronchographically free of disease prior to surgery. These findings suggest that bronchiectasis is a progressive disease and that elective surgery for localized disease probably does not affect its clinical and natural history in this environment.
1975年4月至1978年3月期间，伊巴丹大学学院医院对54例支气管扩张患者进行了治疗。患者性别分布均衡，年龄在5岁至67岁之间，该病在第三和第四个十年发病率最高。三分之一的患者患有结核性支气管扩张伴左肺毁损综合征，另有三分之一患有慢性鼻窦炎，9%的患者患有镰状细胞血红蛋白病。1例卡塔格内综合征、肺曲霉菌病、脊髓灰质炎和异物吸入与支气管扩张有关。在这种环境下，影响该疾病临床病程和预后的因素包括危及生命的咯血、双侧疾病、合并肺脓肿或脓胸、营养不良和慢性贫血。26例患者接受保守治疗，1例死亡；28例患者接受手术治疗，3例死亡。20%的手术患者在术后1至3.5年内，在支气管造影显示术前无病变的肺叶出现复发性支气管扩张。这些发现表明支气管扩张是一种进行性疾病，在这种环境下，针对局限性疾病的择期手术可能不会影响其临床和自然病程。
