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接受扁桃体切除术儿童的免疫学评估

Immunological evaluation of children undergoing tonsillectomy.

作者信息

Gogoi D, Gupta O P, Agarwal M K, Gupta R M

出版信息

J Otolaryngol. 1979 Dec;8(6):508-14.

PMID:529359
Abstract

This study was carried out on 80 patients undergoing tonsillectomy for chronic tonsillitis. Twenty healthy school children in the same age group were investigated for control values. Ten children were also available for evaluation of any immunological change after tonsillectomy. No significant variation was seen in the serum IgG, IgA, and IgM levels before and after tonsillectomy. Peripheral absolute lymphocyte count was higher in the pre-operative cases as compared to the control group, and this count became near normal following tonsillectomy. Skin tests with recall antigens PPD and Candida and contact sensitizing agent 2:4 DNCB showed an improved cell mediated immune response following tonsillectomy.

摘要

本研究对80例因慢性扁桃体炎接受扁桃体切除术的患者进行。对20名同年龄组的健康学童进行调查以获取对照值。另外10名儿童可用于评估扁桃体切除术后的任何免疫变化。扁桃体切除术前和术后血清IgG、IgA和IgM水平未见显著差异。与对照组相比,术前患者外周血绝对淋巴细胞计数较高,扁桃体切除术后该计数接近正常。用回忆抗原PPD、念珠菌以及接触致敏剂2:4二硝基氯苯进行的皮肤试验显示,扁桃体切除术后细胞介导的免疫反应有所改善。

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