Cuadrado R R
Bull World Health Organ. 1965;33(6):803-8.
Recent studies have shown high levels of antibody to the parainfluenza virus group in human sera collected in New England and in other populations in various parts of the world. In view of the importance of animals as reservoirs of viruses affecting man, studies were carried out to assess the level of immunity to the parainfluenza, DA and mumps viruses in domestic animals (cows, swine, dogs, cats, lambs, and sheep) in New England.Antibody levels were determined by the haemagglutination-inhibition test. The results indicated that parainfluenza 3 was the most prevalent followed by parainfluenza 2 and parainfluenza 1; high levels were also found for DA and mumps viruses.A modified agar-gel diffusion test for detecting mumps precipitating antibodies was also investigated. Mumps-immune sera showed a reaction against concentrated soluble antigen. A comparison of the agar-gel diffusion method and standard serological methods, including complement-fixation, neutralization and haemagglutination-inhibition, indicated a significant correlation between the various techniques.
最近的研究表明，在新英格兰地区采集的人类血清以及世界其他地区不同人群的血清中，副流感病毒组抗体水平很高。鉴于动物作为影响人类的病毒宿主的重要性，开展了研究以评估新英格兰地区家畜（牛、猪、狗、猫、羔羊和绵羊）对副流感、DA和腮腺炎病毒的免疫水平。通过血凝抑制试验测定抗体水平。结果表明，副流感3型最为普遍，其次是副流感2型和副流感1型；DA和腮腺炎病毒的抗体水平也很高。还研究了一种用于检测腮腺炎沉淀抗体的改良琼脂凝胶扩散试验。腮腺炎免疫血清对浓缩可溶性抗原有反应。琼脂凝胶扩散法与包括补体结合、中和及血凝抑制在内的标准血清学方法的比较表明，各种技术之间存在显著相关性。
