Collier L H
Bull World Health Organ. 1966;34(2):233-41.
The control of trachoma is still an outstanding problem for many developing countries, despite the widespread use of antibiotics both for prevention and treatment. The isolation of the causal agent in 1957 gave hope of developing a prophylactic vaccine, and in recent years much research has been done on this subject. This article summarizes the requirements that have to be met by a trachoma vaccine and problems arising in its manufacture and testing. A review of the progress made by various workers in this field suggests that, although some vaccines now being tested are partially effective, much remains to be learned about immunity to trachoma and methods of inducing it artificially.
尽管抗生素已广泛用于沙眼的预防和治疗，但对于许多发展中国家而言，沙眼的控制仍是一个突出问题。1957年病原体的分离为开发预防性疫苗带来了希望，近年来针对这一课题已开展了大量研究。本文总结了沙眼疫苗必须满足的要求及其生产和测试中出现的问题。对该领域不同研究人员所取得进展的回顾表明，尽管目前正在测试的一些疫苗有部分效果，但在沙眼免疫及人工诱导免疫的方法方面仍有许多有待了解之处。
