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5-羟色胺对大鼠棉球局部炎症反应的影响。

The effect of 5-hydroxytryptamine on the cotton pellet local inflammatory response in the rat.

作者信息

Bianchine J R, Eade N R

出版信息

J Exp Med. 1967 Mar 1;125(3):501-10. doi: 10.1084/jem.125.3.501.

DOI:10.1084/jem.125.3.501
PMID:5297527
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2138287/
Abstract

The cotton pellet technique was used to evaluate the effect of 5-HT and certain related compounds on granuloma formation in the rat. 5-HT (10 mg/kg) significantly decreased granuloma formation, significantly increased adrenal weight, and significantly decreased thymus weight in normal rats, and significantly decreased granuloma formation and thymus weight in sham-operated rats. On the other hand, 5-HT (10 mg/kg) significantly increased granuloma weight in adrenalectomized rats. Methysergide (1 mg/kg) blocked the inhibitory effect of 5-HT on granuloma formation as well as the changes in weight of adrenal and thymus glands. 5-HIAA (11 mg/kg) and 5-HTP (13 mg/kg) failed to alter granuloma formation.

摘要

采用棉球法评估5-羟色胺（5-HT）及某些相关化合物对大鼠肉芽肿形成的影响。5-HT（10毫克/千克）显著减少正常大鼠的肉芽肿形成，显著增加肾上腺重量，并显著降低胸腺重量，在假手术大鼠中显著减少肉芽肿形成和胸腺重量。另一方面，5-HT（10毫克/千克）显著增加肾上腺切除大鼠的肉芽肿重量。麦角新碱（1毫克/千克）阻断了5-HT对肉芽肿形成的抑制作用以及肾上腺和胸腺重量的变化。5-羟吲哚乙酸（5-HIAA，11毫克/千克）和5-羟色氨酸（5-HTP，13毫克/千克）未能改变肉芽肿形成。

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J Pharm Pharmacol. 1965 Jan;17:10-4. doi: 10.1111/j.2042-7158.1965.tb07559.x.
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J Pathol Bacteriol. 1964 Apr;87:325-32. doi: 10.1002/path.1700870212.
4
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5
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7
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