Burton G J
Bull World Health Organ. 1967;37(2):317-22.
Investigations in Guyana in 1961-63 showed that Wuchereria bancrofti was the only filarial parasite causing elephantiasis and that Culex pipiens fatigans was the primary vector. Mansonia titillans and Anopheles aquasalis were found to be secondary vectors.C. p. fatigans bred primarily in pit latrines and secondarily in the clean, confined water of drums and barrels near latrines. No breeding occurred in the relatively clean open water of trenches, ditches and drains.Of 21016 mosquitos collected from houses, 39.9% were found resting on walls, 34.9% on clothing and other hanging objects, and 23.4% on or under furniture. Of 15 622 female mosquitos caught, 9.6% contained W. bancrofti parasites and 0.5% contained infective larvae. The flight range was found to be about half a mile (0.8 km).Control was achieved by a combination of antimosquito (spraying with gas-oil) and antiparasitic (chemotherapy with diethylcarbamazine) measures, which reduced the average infection rates in the Buxton control area from 17.7% to 2.2%. Over the same period, breeding in drums dropped from 14%-25% to 4.7%, even though the drums were not treated or covered.
1961年至1963年在圭亚那进行的调查显示，班氏吴策线虫是导致象皮病的唯一丝虫寄生虫，致倦库蚊是主要传播媒介。蒂氏曼蚊和海滨按蚊被发现为次要传播媒介。致倦库蚊主要在坑式厕所繁殖，其次在厕所附近桶和罐中干净、封闭的水中繁殖。在沟渠和排水渠相对干净的开阔水域中未发现其繁殖。从房屋中收集的21016只蚊子中，39.9%被发现停歇在墙壁上，34.9%停歇在衣物和其他悬挂物上，23.4%停歇在家具上或家具下。在捕获的15622只雌蚊中，9.6%携带班氏吴策线虫寄生虫，0.5%携带感染性幼虫。发现其飞行范围约为半英里（0.8公里）。通过灭蚊（用粗柴油喷洒）和抗寄生虫（用乙胺嗪进行化疗）措施相结合实现了控制，这使巴克斯顿控制区的平均感染率从17.7%降至2.2%。在同一时期，即使桶未进行处理或覆盖，桶中的繁殖率也从14% - 25%降至4.7%。
