眼镜蛇毒磷脂酶A2对红细胞膜脂质的作用。
Action of cobra venom phospholipase A2 toward lipids of erythrocyte membranes.
作者信息
Adamich M, Dennis E A
出版信息
Prog Clin Biol Res. 1979;30:515-21.
PMID:531042
Abstract
The activity of cobra venom phospholipase A2 toward phospholipids in erythrocyte membranes is enhanced significantly following ghosting of the membrane. The specificity observed is phosphatidylethanolamine greater than phosphatidylcholine and is the reverse of that expected from model studies with individual phospholipids. It is shown, utilizing phospholipid mixtures, that the activity and specificity of cobra venom phospholipase A2 is dependent on the presence of other lipids and their organization.
摘要
眼镜蛇毒磷脂酶A2对红细胞膜中磷脂的活性在膜空泡化后显著增强。观察到的特异性是磷脂酰乙醇胺大于磷脂酰胆碱，这与对单个磷脂进行模型研究所预期的结果相反。利用磷脂混合物表明，眼镜蛇毒磷脂酶A2的活性和特异性取决于其他脂质的存在及其组织形式。
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