Holt J M, Gear M W, Warner G T
Gut. 1970 Oct;11(10):847-50. doi: 10.1136/gut.11.10.847.
The role of chronic blood loss in the pathogenesis of postgastrectomy iron-deficiency anaemia was assessed by measurements of blood loss over periods of up to three months, using a whole-body counter and (59)Fe. Eleven patients were investigated and eight of these were selected because of a history of iron-deficiency anaemia. Six were shown to be losing blood abnormally, five at a rate of over 150 ml per month. None of the three patients without a history of anaemia lost more than 60 ml per month. At gastroscopy contact bleeding from the mucosa of the gastric remnant was observed in four of the six patients losing blood. The results indicate that in some patients chronic blood loss plays an important role in the pathogenesis of postgastrectomy iron-deficiency anaemia.
通过使用全身计数器和(59)铁对长达三个月的失血量进行测量,评估了慢性失血在胃切除术后缺铁性贫血发病机制中的作用。对11名患者进行了研究,其中8名因有缺铁性贫血病史而被选中。有6名患者显示有异常失血,其中5名每月失血量超过150毫升。三名无贫血病史的患者每月失血量均不超过60毫升。在胃镜检查中,6名失血患者中有4名观察到胃残余黏膜有接触性出血。结果表明,在一些患者中,慢性失血在胃切除术后缺铁性贫血的发病机制中起重要作用。