加尔各答一个半封闭社区中霍乱再接种的血清学反应。
Serological response to cholera revaccination in a semi-closed community in Calcutta.
作者信息
Sinha R, Deb B C, Ganguly R, De S P, Abou-Gareeb A H, Shrivastava D L
出版信息
Bull World Health Organ. 1970;43(3):407-12.
Serological response to cholera revaccination has been studied in a semi-closed community consisting of individuals mostly in the 2-20-years age-group. The subjects had been inoculated against cholera every year at the beginning of the local epidemic season. Pre- and post-vaccination sera were obtained from 29 subjects inoculated with cholera vaccine (test group) and 28 from subjects inoculated with TAB vaccine (control group). These sera were tested for vibriocidal and agglutination titres. The geometrical means of the vibriocidal and agglutination titres of the post-vaccination sera in the test group rose by 490% and 463% respectively. This booster effect was observed mostly in individuals in the 2-14-years age-group, who had low titres (vibriocidal </=320 and agglutination </=40) in their prevaccination samples. Revaccination, therefore, appears to be useful as a booster for individuals having low titres.
在一个半封闭社区中，对霍乱再接种的血清学反应进行了研究，该社区的个体大多在2至20岁年龄组。每年在当地流行季节开始时，这些受试者都接种霍乱疫苗。从29名接种霍乱疫苗的受试者（试验组）和28名接种伤寒、副伤寒甲、乙三联疫苗（TAB疫苗）的受试者（对照组）中获取接种前和接种后的血清。对这些血清进行了杀弧菌和凝集效价检测。试验组接种后血清的杀弧菌和凝集效价几何平均值分别上升了490%和463%。这种增强效应主要在2至14岁年龄组的个体中观察到，他们在接种前样本中的效价较低（杀弧菌效价≤320，凝集效价≤40）。因此，再接种似乎对效价较低的个体作为一种增强剂是有用的。
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