Sainio K, Putkonen P T
Electroencephalogr Clin Neurophysiol. 1975 Dec;39(6):663-6. doi: 10.1016/0013-4694(75)90080-2.
In rabbits experimental cerebral ischemia of 4-6 min was followed by degradation of the electroencephalographic sleep-waking cycle, as determined from 3 h afternoon records: I. Hyposomnia i.e., reduction of slow wave and paradoxical sleep lasting for about 2 days, was seen, with gradual normalization in case of survival. II. In the first postischemic days abundant 14-17 c/sec spindles appeared in the motor cortex against a low voltage desynchronized background, making the EEG of waking qualitatively different from control records. The results are discussed with reference to polygraphic studies in comatose patients, EEG phenomenology of drowsiness, and cerebral monoamines.
在兔子身上，实验性脑缺血4 - 6分钟后，根据下午3小时的记录，脑电图的睡眠 - 觉醒周期出现退化：I. 出现睡眠减退，即慢波睡眠和异相睡眠减少，持续约2天，若存活则逐渐恢复正常。II. 在缺血后的最初几天，运动皮层在低电压去同步化背景下出现大量14 - 17次/秒的纺锤波，使清醒时的脑电图在性质上与对照记录不同。结合昏迷患者的多导睡眠图研究、嗜睡的脑电图现象学以及脑单胺类物质对结果进行了讨论。
