Capron J P, Lemay J L, Gontier M F, Dupas J L, Capron-Chivrac D, Lorriaux A
Scand J Gastroenterol. 1979;14(8):987-92.
In a prospective study of liver function in 19 patients with Crohn's disease, examination of liver biopsies showed a sinusoidal dilatation in 16 patients. This dilatation was moderate in 5 cases and pronounced in 6 cases and was associated with a closely parallel dilatation of the centrilobular vein. There was no correlation between these diffuse vascular changes and the site of the bowel disease, the clinical presentation, and the course of the disease. The pathogenesis of this sinusoidal dilatation is unknown.
在一项对19例克罗恩病患者肝功能的前瞻性研究中，肝活检检查显示16例患者存在肝血窦扩张。这种扩张在5例患者中为中度，在6例患者中为重度，且与小叶中心静脉的紧密平行扩张相关。这些弥漫性血管变化与肠道疾病的部位、临床表现及病程之间均无相关性。这种肝血窦扩张的发病机制尚不清楚。
