Bradley G W, Nicholls A C, Banfield L
Scand J Respir Dis. 1979 Aug;60(4):176-83.
Two years' experience of a simple serological test for the diagnosis of tuberculosis has been evaluated. This test fails to distinguish clearly between tuberculous and non-tuberculous patients. There is an unacceptably high incidence of false positive and false negative results, although the latter would be reduced by taking the highest titre values of several samples from one patient. Modification of the test to eliminate IgM agglutination produced a marked fall in false positive results. These preliminary results suggest that this modified test is more useful, in that a positive test is a strong indication of tuberculosis. The use of a Coombs' test to agglutinate incomplete complexes did not improve results.
一项用于诊断结核病的简单血清学检测已历经两年评估。该检测无法清晰区分结核患者与非结核患者。假阳性和假阴性结果的发生率高得令人无法接受，不过从一名患者的多个样本中取最高滴度值可减少后者的出现。对该检测进行修改以消除IgM凝集，使得假阳性结果显著下降。这些初步结果表明，这种修改后的检测更有用，因为检测呈阳性强烈提示患有结核病。使用库姆斯试验凝集不完全复合物并未改善检测结果。
