Stiksa G, Korsgaard R, Simonsson B G
Scand J Respir Dis. 1979 Aug;60(4):197-205.
A total of 121 pleurodeses using instillations of quinacrine (mepacrine) in patients with recurrent pleural effusion were performed. All but three patients suffered from pleural malignancy. A comparison was made between the results achieved by repeated thoracenteses (73 cases) and by simultaneous tube drainage (48 cases). Tube drainage shortened the treatment and lowered the number of painful interventions. There was no difference in the quality of pleurodesis achieved by the two methods. The treatment failed in 12% of patients treated by repeated thoracenteses and in 14% of those treated by tube drainage. Patients with pleurodeses survive longer than non-treated subjects and have a considerably better quality of life.
对121例复发性胸腔积液患者进行了使用喹吖因（米帕林）注入的胸膜固定术。除3例患者外，其余均患有胸膜恶性肿瘤。对反复胸腔穿刺术（73例）和同期置管引流术（48例）的结果进行了比较。置管引流缩短了治疗时间并减少了痛苦的干预次数。两种方法实现的胸膜固定质量没有差异。反复胸腔穿刺术治疗的患者中有12%治疗失败，置管引流术治疗的患者中有14%治疗失败。接受胸膜固定术的患者比未接受治疗的患者存活时间更长，生活质量也明显更好。
