Selroos O, Sellergren T L
Scand J Respir Dis. 1979 Aug;60(4):215-21.
Thirty-nine sarcoidosis patients with pulmonary infiltrations (stage II) of less than 5 years duration and not treated earlier with corticosteroids were randomly allocated for treatment with methylprednisolone for 7 months or for observation without therapy. Every other treated patient was given the drugs daily and every other followed an alternate-day regimen. After 7 months the chest radiographic finding, the forced vital capacity and the diffusion capacity for carbon monoxide were superior in the treated group. There was no difference between the two drug regimens. After 24 and 48 months no statistically significant differences between the untreated and the treated groups were found.
39例病程少于5年且未接受过皮质类固醇治疗的肺部浸润（II期）结节病患者被随机分为两组，一组接受甲基强的松龙治疗7个月，另一组不接受治疗仅进行观察。每隔一位接受治疗的患者每日给药，其余患者采用隔日给药方案。7个月后，治疗组的胸部X线表现、用力肺活量和一氧化碳弥散量均优于未治疗组。两种给药方案之间无差异。24个月和48个月后，未治疗组和治疗组之间未发现统计学上的显著差异。
