Artenstein M S, Branche W C, Zimmerly J G, Cohen R L, Tramont E C, Kasper D L, Harkins C
Bull World Health Organ. 1971;45(3):283-6.
Studies with 4 lots of group A meningococcal polysaccharides in 458 adult human volunteers showed that such vaccines are nontoxic and highly immunogenic. Comparisons of jet injection and subcutaneous (needle) methods of administration showed that both were equally immunogenic.
对458名成年人类志愿者使用4批A群脑膜炎球菌多糖进行的研究表明,此类疫苗无毒且具有高度免疫原性。对喷射注射和皮下(针剂)给药方法的比较表明,二者的免疫原性相同。