Lejkina E S
Bull World Health Organ. 1965;32(5):699-708.
The pattern of antibody response to Ascaris in the blood of experimentally infected human beings, pigs and laboratory animals indicates that immunity to ascariasis develops mainly under the effect of migrating larvae. The antibody can be demonstrated in the microprecipitation test on live larvae in vitro and in the agglutination test with carmine-adsorbed antigen. The antibodies can be detected 5-10 days after infection and remain in the blood for 90-100 days.The pattern observed in the increase in antibody titre permits the use of serological reactions both for diagnosis of the early phase of ascariasis and for investigation of a number of problems in the epidemiology of this infection. Application of immunological methods in mass surveys of the population makes it possible to correct existing conceptions of the duration of the season of infection, the extent of infection and the risk of infection in foci of ascariasis.
在实验感染的人类、猪和实验动物血液中，对蛔虫的抗体反应模式表明，对蛔虫病的免疫力主要在移行幼虫的作用下发展。抗体可在体外对活幼虫的微量沉淀试验以及用洋红吸附抗原的凝集试验中得到证实。感染后5 - 10天可检测到抗体，抗体在血液中持续90 - 100天。观察到的抗体滴度增加模式使得血清学反应可用于蛔虫病早期阶段的诊断以及该感染流行病学中一些问题的研究。免疫方法在人群大规模调查中的应用使得有可能纠正关于蛔虫病感染季节持续时间、感染程度以及蛔虫病疫源地感染风险的现有观念。
