[免疫球蛋白制剂中的滋养层β-球蛋白]
[Trophoblastic beta-globulin in immunoglobulin preparations].
作者信息
Migunov V N, Pozina I M, Minakova L V, Prokopenko P G, Tatarinov Iu S
出版信息
Zh Mikrobiol Epidemiol Immunobiol. 1983 Jan(1):107-10.
The content of trophoblastic beta-globulin in 142 lots of commercial immunoglobulin preparations from 20 manufacturers, produced from placental, abortion and donor blood sera, has been studied. 83% of lots from abortion blood serum and 94% of lots from placental blood serum have been found to contain the admixture of this beta-globulin, its concentration in the lots from placental blood serum being significantly higher. The method for the detection of trophoblastic beta-globulin may be used for evaluating the quality of immunoglobulin preparations as it indicates the degree of their purification from placental proteins.
对来自20家制造商的142批市售免疫球蛋白制剂进行了研究，这些制剂由胎盘、流产和供血者血清制成。已发现83%的流产血清批次和94%的胎盘血清批次含有这种β-球蛋白混合物，其在胎盘血清批次中的浓度明显更高。滋养层β-球蛋白的检测方法可用于评估免疫球蛋白制剂的质量，因为它表明了制剂从胎盘蛋白中纯化的程度。
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