Penneys N S, Wiley H E
Arch Dermatol. 1979 Dec;115(12):1427-8.
Four patients with systemic lupus erythematosus (SLE) had a vesicobullous eruption that histologically resembled dermatitis herpetiformis. Immunofluorescence microscopy patterns in the skin studied in three patients, however, were characteristic of SLE. Treatment of the underlying collagen-vascular disease improved the eruption, while recurrence coincided with exacerbation of the systemic disease. This distinctive lesion is an important parameter of SLE activity.
四名系统性红斑狼疮(SLE)患者出现了水疱大疱性皮疹,组织学上类似于疱疹样皮炎。然而,对三名患者皮肤进行的免疫荧光显微镜检查结果具有SLE的特征。对潜在的胶原血管疾病进行治疗后皮疹有所改善,而复发则与全身性疾病的加重同时发生。这种独特的皮损是SLE活动的一个重要指标。