Girardet J P, Mathe J C, Bensman A
Arch Fr Pediatr. 1979 Jul-Aug;36(7):656-64.
Six children aged between 10 months and 13 years with allergic vasculitis are described. The features they had in common were necrotic skin lesions, involvement of various viscera and signs of hypersensitivity reactions. Histological changes of allergic vasculitis were present in the small vessels of the skin. This condition has features in common with both polyarteritis nodosa and with anaphylactoid purpura. Severe cases that do not respond to corticosteroids may respond to immuno-suppression with cyclophosphamide.
本文描述了6名年龄在10个月至13岁之间的过敏性血管炎患儿。他们的共同特征为皮肤坏死性病变、多脏器受累及超敏反应体征。皮肤小血管存在过敏性血管炎的组织学改变。这种疾病与结节性多动脉炎及过敏性紫癜均有共同特征。对皮质类固醇治疗无反应的重症病例,使用环磷酰胺免疫抑制治疗可能有效。