[先天性梅毒期间的膜外肾小球肾炎]
[Extramembranous glomerulonephritis during congenital syphilis].
作者信息
Palcoux J B, Gaulme J, Deméocq F, Bétail G, Beytout D, Dalens B
出版信息
Arch Fr Pediatr. 1979 Jul-Aug;36(7):691-5.
PMID:533348
Abstract
A 3 month old girl with congenital syphilis presented with the nephrotic syndrome due to extra membranous glomerulonephritis. The presence of the first component of the classical pathway of complement activation (C1q) in the glomerular deposits and the antitreponemal antibodies in circulating cryoglobulins (titre 1 : 320) support the hypothesis that immune complexes are responsbile for the glomerulonephritis in congenital syphilis.
摘要
一名3个月大的先天性梅毒女童因膜性增生性肾小球肾炎出现肾病综合征。肾小球沉积物中补体激活经典途径的第一成分（C1q）的存在以及循环冷球蛋白中的抗梅毒螺旋体抗体（滴度1:320）支持了免疫复合物是先天性梅毒肾小球肾炎病因的假说。
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