Losito A, Bucciarelli E, Massi-Benedetti F, Lato M
Clin Nephrol. 1979 Jul;12(1):32-7.
The glomerulonephritis of congenital syphilis is thought to be immune-complex mediated. We describe a case of C. S. in whom the only manifestation was a glomerulonephritis. Immunopathogenic studies allowed the identification of treponemal antigen in glomeruli. The elution of immunoglobulins from renal tissue showed that glomerular deposits contained antitreponemal antibodies. Cryoglobulins with antitreponemal activity were also isolated from the patient's serum.
先天性梅毒的肾小球肾炎被认为是由免疫复合物介导的。我们描述了一例先天性梅毒患者，其唯一表现为肾小球肾炎。免疫病理学研究发现肾小球中有梅毒螺旋体抗原。从肾组织洗脱免疫球蛋白显示，肾小球沉积物中含有抗梅毒螺旋体抗体。还从患者血清中分离出具有抗梅毒螺旋体活性的冷球蛋白。
