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体外培养的人口腔鳞状细胞癌

Human oral squamous cell carcinoma in in vitro culture.

作者信息

Anniko M

出版信息

Arch Otorhinolaryngol. 1979;225(1):21-6. doi: 10.1007/BF00455871.

DOI:10.1007/BF00455871
PMID:533445
Abstract

Human biopsy specimens from squamous cell carcinomas in the oral cavity were explanted to an in vitro system for organ culture. Carcinoma cells in great number were observed after 2 weeks in vitro. A considerable variability in cell survival occurred after approximately 1 week. This period of time is, however, sufficient to perform experimental manipulation of the tumor tissue, e.g., testing of chemosensitivity, radiation effects, etc.

摘要

取自口腔鳞状细胞癌的人体活检标本被移植到体外器官培养系统中。体外培养2周后观察到大量癌细胞。大约1周后细胞存活率出现了相当大的差异。然而,这段时间足以对肿瘤组织进行实验操作,例如测试化学敏感性、辐射效应等。

相似文献

1
Human oral squamous cell carcinoma in in vitro culture.体外培养的人口腔鳞状细胞癌
Arch Otorhinolaryngol. 1979;225(1):21-6. doi: 10.1007/BF00455871.
2
Collagenase activity in epidermoid carcinoma of the oral cavity and larynx.口腔和喉表皮样癌中的胶原酶活性。
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J Dent Res. 1966 Nov-Dec;45(6):1804-9. doi: 10.1177/00220345660450063701.
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Role of hyaluronan synthase 2 to promote CD44-dependent oral cavity squamous cell carcinoma progression.透明质酸合酶 2 促进 CD44 依赖的口腔鳞状细胞癌进展的作用。
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[Chemosensitivity testing of oral and maxillofacial cancer with biopsy specimens].[口腔颌面部癌活检标本的化学敏感性测试]
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本文引用的文献

1
[Use of the vitelline membrane of the chicken egg in organotypic culture. I. Technic and possibilities].
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2
A simple radiochemical assay of inhibition by chemotherapeutic agents of precursor incorporation into biopsy samples, effusions, and leukocyte preparations.一种用于检测化疗药物对活检样本、积液和白细胞制剂中前体掺入的抑制作用的简单放射化学测定法。
Cancer Res. 1968 Nov;28(11):2228-31.
3
Effect of chemotherapeutic agents and hormones on organ cultures of human tumours.化疗药物和激素对人肿瘤器官培养物的影响。
Eur J Cancer (1965). 1968 Mar;4(1):39-44. doi: 10.1016/0014-2964(68)90068-6.
4
[Experiences with individual cytostatic therapy of malignant tumors following pretherapeutic sensitivity test to cytostatics in vitro (oncobiogram)].[在体外对细胞抑制剂进行治疗前敏感性测试(肿瘤生物图谱)后进行恶性肿瘤个体化细胞抑制剂治疗的经验]
Arch Geschwulstforsch. 1970;35(1):44-53.