Pearman J W
Br J Urol. 1979 Oct;51(5):367-74. doi: 10.1111/j.1464-410x.1979.tb02888.x.
Two groups of patients with acute spinal cord trauma had initial bladder management by standard non-touch techniques of intermittent catheterisation. Twenty-two patients (17 males and 5 females) had kanamycin-colistin solution instilled into the bladder at the end of each catheterisation, and 25 patients (21 males and 4 females) were not given these instillations. The incidence of significant bacteriuria during intermittent catheterisation of both males and females receiving the instillations was only half the incidence of those not receiving the instillations. Also, a significantly higher proportion of males receiving the instillations did not have any episodes of significant bacteriuria compared with those not receiving the instillations, and the same trend was evident in the small number of female patients. It is recommended that patients should have kanamycin-colistin bladder instillations when they are being intermittently catheterised.
两组急性脊髓损伤患者最初采用标准的非接触式间歇性导尿技术进行膀胱管理。22例患者（17例男性和5例女性）在每次导尿结束时将卡那霉素 - 黏菌素溶液注入膀胱，25例患者（21例男性和4例女性）未进行这些灌注。接受灌注的男性和女性在间歇性导尿期间显著菌尿的发生率仅为未接受灌注者的一半。此外，接受灌注的男性中无显著菌尿发作的比例明显高于未接受灌注的男性，在少数女性患者中也有同样的趋势。建议患者在进行间歇性导尿时应进行卡那霉素 - 黏菌素膀胱灌注。
