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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Newell P C, Tucker R G

Biochem J. 1966 Aug;100(2):512-6. doi: 10.1042/bj1000512.

Growth of Salmonella typhimurium LT2 in the presence of adenosine was shown to cause enormous synthesis of thiamine in washed-cell suspensions. 2. Evidence that this was due to de-repression and not an accumulation of precursors was obtained by using a mutant blocked in the biosynthesis of the thiazole moiety, which showed a similarly large synthesis of the pyrimidine of thiamine. 3. The specific requirements for a source of energy, nitrogen and sulphur were investigated, and indicated new synthesis in this system.

鼠伤寒沙门氏菌LT2在腺苷存在的情况下生长，结果表明，在洗涤过的细胞悬液中会大量合成硫胺素。2. 通过使用在噻唑部分生物合成中受阻的突变体，获得了证据，表明这是由于去阻遏而非前体积累所致，该突变体显示出硫胺素嘧啶部分同样大量的合成。3. 研究了对能量、氮和硫来源的特定需求，并表明该系统中有新的合成过程。

Newell P C, Tucker R G

Biochem J. 1966 Aug;100(2):512-6. doi: 10.1042/bj1000512.

Growth of Salmonella typhimurium LT2 in the presence of adenosine was shown to cause enormous synthesis of thiamine in washed-cell suspensions. 2. Evidence that this was due to de-repression and not an accumulation of precursors was obtained by using a mutant blocked in the biosynthesis of the thiazole moiety, which showed a similarly large synthesis of the pyrimidine of thiamine. 3. The specific requirements for a source of energy, nitrogen and sulphur were investigated, and indicated new synthesis in this system.

鼠伤寒沙门氏菌LT2在腺苷存在的情况下生长，结果表明，在洗涤过的细胞悬液中会大量合成硫胺素。2. 通过使用在噻唑部分生物合成中受阻的突变体，获得了证据，表明这是由于去阻遏而非前体积累所致，该突变体显示出硫胺素嘧啶部分同样大量的合成。3. 研究了对能量、氮和硫来源的特定需求，并表明该系统中有新的合成过程。