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大肠杆菌对大肠菌素E-2的致死吸附动力学

Kinetics of lethal adsorption of colicin E-2 by Escherichia coli.

作者信息

Shannon R, Hedges A J

出版信息

J Bacteriol. 1967 Apr;93(4):1353-9. doi: 10.1128/jb.93.4.1353-1359.1967.

Abstract

The kinetics of lethal adsorption of colicin E2 by Escherichia coli C6 were studied by means of survivor plots. These were determined by a method which allowed rapid sampling of the reaction mixture and estimation of approximate confidence limits for the plotted data. The results were consistent with the predictions of a hypothetical model that assumed a single-hit mechanism of colicin action upon a bacterial population whose cells varied in their number of specific (lethal) receptors for colicin. The possibility of nonlethal adsorption is discussed.

摘要

通过存活曲线研究了大肠杆菌C6对大肠杆菌素E2的致死吸附动力学。这些曲线是通过一种方法确定的,该方法允许对反应混合物进行快速采样,并估计所绘制数据的近似置信限。结果与一个假设模型的预测一致,该模型假设大肠杆菌素对细菌群体的作用是单打击机制,其细胞对大肠杆菌素的特异性(致死)受体数量不同。文中还讨论了非致死吸附的可能性。

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