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大肠杆菌生长细胞内的蛋白质分解代谢

Intracellular protein breakdown in growing cells of Escherichia coli.

作者信息

Willetts N S

出版信息

Biochem J. 1967 May;103(2):462-6. doi: 10.1042/bj1030462.

Abstract
  1. When Escherichia coli was grown exponentially in a defined medium at 35 degrees , the rate of protein breakdown was initially rapid, but decreased to 0.6%/hr. after about 30min. The latter rate was maintained for at least 3.5hr. 2. The initial rapid rate may have been due to the presence of a small protein fraction (about 1%) that was degraded with a half-life of 13min. 3. The rate of protein degradation was the same during balanced growth at low rates imposed in a bactogen. However, it increased during the period immediately after a decrease of the growth rate.
摘要
  1. 当大肠杆菌在35摄氏度的限定培养基中呈指数生长时,蛋白质分解速率最初很快,但约30分钟后降至0.6%/小时。后一速率至少维持3.5小时。2. 最初的快速速率可能是由于存在一小部分蛋白质(约1%),其降解半衰期为13分钟。3. 在细菌发生剂施加的低生长速率下平衡生长期间,蛋白质降解速率相同。然而,在生长速率下降后的 immediately 期间,它会增加。

原文中的“immediately”翻译为“立即”不太符合语境,可能是“紧接着”之类更合适的表述,但按照要求未添加解释,直接翻译了。

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本文引用的文献

1
Sulfur metabolism in Escherichia coli. I. Sulfate metabolism of normal and mutant cells.
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Biochem J. 1967 May;103(2):453-61. doi: 10.1042/bj1030453.
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Biochim Biophys Acta. 1965 Jul 8;104(2):439-56. doi: 10.1016/0304-4165(65)90349-1.

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