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三叉神经痛与多发性硬化症:一例手术病例中斑块的显示

Trigeminal neuralgia and multiple sclerosis: demonstration of the plaque in an operative case.

作者信息

Lazar M L, Kirkpatrick J B

出版信息

Neurosurgery. 1979 Dec;5(6):711-7. doi: 10.1227/00006123-197912000-00013.

DOI:10.1227/00006123-197912000-00013
PMID:534082
Abstract

Trigeminal neuralgia is unique to humans. The most common cause seems to be an injury to the myelin of the trigeminal nerve root entry zone as it extends for several millimeters lateral to the pons. Jannetta has developed an elegant retromastoid microsurgical approach to this region. He has identified a compression-distortion phenomenon of this nerve root entry zone, usually from an anomalous position of the superior cerebella artery. Trigeminal neuralgia can also occur in association with multiple sclerosis, when the plaque lies in this same location. The historical evidence for this explanation is reinforced by the electron microscopic demonstration of the plaque in this region in a patient with multiple sclerosis who was suffering from tic douloureux. (Neurosurgery, 5: 711--717, 1979).

摘要

三叉神经痛是人类所特有的疾病。最常见的病因似乎是三叉神经根进入区的髓鞘受到损伤,该区域在脑桥外侧延伸数毫米。詹内塔已经开发出一种针对该区域的精妙的乳突后显微手术方法。他发现了该神经根进入区的压迫 - 变形现象,通常是由于小脑上动脉位置异常所致。三叉神经痛也可与多发性硬化症相关联,此时斑块就位于同一位置。一名患有三叉神经痛的多发性硬化症患者,其该区域斑块的电子显微镜显示结果进一步证实了这一解释的历史证据。(《神经外科学》,第5卷:711 - 717页,1979年)

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Diffusion tensor imaging of the trigeminal nerve in patients with trigeminal neuralgia due to multiple sclerosis.多发性硬化所致三叉神经痛患者的三叉神经扩散张量成像
Neuroradiology. 2015 Mar;57(3):259-67. doi: 10.1007/s00234-014-1463-7. Epub 2014 Nov 18.
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Pain and multiple sclerosis: pathophysiology and treatment.
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Curr Neurol Neurosci Rep. 2013 Jan;13(1):320. doi: 10.1007/s11910-012-0320-5.
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Trigeminal neuralgia and other neuropathic pain syndromes of the head and face.三叉神经痛及其他头面部神经病理性疼痛综合征。
Curr Pain Headache Rep. 2002 Apr;6(2):115-24. doi: 10.1007/s11916-002-0007-8.
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Microvascular decompression for trigeminal neuralgia: comments on a series of 250 cases, including 10 patients with multiple sclerosis.三叉神经痛的微血管减压术:对250例病例的评论,包括10例多发性硬化症患者。
J Neurol Neurosurg Psychiatry. 2000 Jan;68(1):59-64. doi: 10.1136/jnnp.68.1.59.
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