Zipser D
Science. 1967 Sep 8;157(3793):1176-7. doi: 10.1126/science.157.3793.1176.
Intracodon recombination is used to orient the nonsense codons UGA, UAG, and UAA on the genetic map of the (lactose) lac operon of Escherichia coli. The 5'-end of these triplets is toward the operator end of the operon. A hypothesis is presented to explain the fact that the frequency of recombination between adjacent nucleotides is many times lower than expected.
密码子内重组被用于在大肠杆菌(乳糖)lac操纵子的遗传图谱上定位无义密码子UGA、UAG和UAA。这些三联体的5'端朝向操纵子的操纵基因端。本文提出了一个假说,以解释相邻核苷酸之间的重组频率比预期低很多倍这一事实。